Journal of the Korean Physical Society

pISSN 0374-4884 eISSN 1976-8524
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Article

Cross-Disciplinary Physics and Related Areas of Science and Technology

J. Korean Phy. Soc. 2010; 56(5): 1532-1536

Published online May 14, 2010     https://doi.org/10.3938/jkps.56.1532

Copyright © The Korean Physical Society.

 Longitudinal Water Proton Relaxivities of Ultra Small 3d and 4f Transition Metal Oxide Nanoparticles

Gang Ho Lee, Eun Sook Choi, Ja Young Park, Krishna Kattel, Wenlong Xu, Myung Ju Baek, Joo Hyun Kim, Yongmin Chang, Tae Jeong Kim

Abstract

 We report the longitudinal water proton relaxivities (r1) of several 3d and 3f transition metal oxide nanoparticles. These include ultra small iron oxide, manganese oxide, europium oxide, gadolinium oxide, and dysprosium oxide nanoparticles. The nanoparticles ranged from 1.0 to 3.0 nm in diameter. Ultra small metal oxide nanoparticles with metal ions of high and pure S-state electron magnetic moments showed high r1 relaxivities. The measured relaxivities indicate that ultra small gadolinium oxide nanoparticles with a high r1 relaxivity of 12.6 mM-1s-1 may be suitable for a sensitive T1 MRI contrast agent.

Keywords: Ultra small, Metal oxide nanoparticle, Longitudinal relaxivity, MRI contrast agent

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